| 產(chǎn)品詳情 |
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| Antigenic Specificity | Tyrosinase |
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| Clone | TYR/2024R |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | Protein A/G purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IHC-Fx, SDS-PAGE |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Tyrosinase Antibody (clone TYR/2024R) LS-C751406. Recognizes a cluster of proteins between 70-80 kDa , identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful marker for melanocytes and melanomas. |
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| Immunogen | Recombinant full-length human tyrosinase (TYR) protein. Antigen Molecular Weight: 70-80 kDa |
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| Other Names | TYR, CMM8, LB24-AB, SHEP3, SK29-AB, Monophenol monooxygenase, Tumor rejection antigen AB, OCA1A, Tyrosinase, OCAIA |
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| Gene, Accession # | TYR, Gene ID: 7299 |
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| Catalog # | LS-C751406 |
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| Price | |
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| Order / More Info | Tyrosinase Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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