| 產(chǎn)品詳情 |
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| Product Name | EXP-3174 |
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| Description | EXP-3174 is a physiologically active metabolite of losartan, produced by cytochrome P450 isoforms in the liver. EXP-3174 is a potent angiotensin II receptor, type 1 (AT1) antagonist (Kis = 0.57 and 0.67 nM for rat and human forms, respectively), producing a depressor response and vasodilatation. When administered intravenously, losartan carboxylic acid is more potent and has a longer duration of action than losartan. However, the metabolite has very low oral bioavailability. MW: 436.9. Purity ≥98% by HPLC |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazole-5-carboxylic acid; Losartan carboxylic acid |
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| Gene, Accession, CAS # | CAS: 124750-92-1 |
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| Catalog # | 9672-25 |
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| Order / More Info | EXP-3174 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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