| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | Gliclazide |
|---|
| Description | A sulfonylurea and an inhibitor of pancreatic β-cell KATP channels (IC50 = 184 nM for murine β-cells); selective for pancreatic β-cell over cardiac and arterial smooth muscle cell KATP channels (IC50s = 19.5 and 37.9 μM, respectively); increases insulin-induced glucose uptake and GLUT4 translocation to the plasma membrane in a differentiated 3T3L1 adipocyte model of insulin resistance induced by hydrogen peroxide at 5 μM; reduces LDL oxidation by HASMCs, decreasing TBARS content and 8-isoprostane levels at 5 and 10 μg/ml; decreases oxidized LDL-induced HASMC proliferation and monocyte adhesion at 1-10 μg/ml; reduces serum glucose levels and increases glucose uptake by isolated rat hindquarters in a model of diabetes induced by STZ at 5mg/kg |
|---|
| Size | 5 g |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | Diabezidum Diabrezide Diabyl Diaprel Glimicron Glinormax Glyzide 1702 S 852 SE GLUT 4 3T3 L1 low density lipoprotein S1702 S852 SE1702 Diamicron |
|---|
| Gene, Accession, CAS # | CAS: 21187-98-4 |
|---|
| Catalog # | 25503-5 |
|---|
| Price | |
|---|
| Order / More Info | Gliclazide from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|