| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | NU 6140 |
|---|
| Description | Cyclin-dependent kinase 2 (cdk2) inhibitor (IC50 values are 0.42 - 1.1 μM). Displays some selectivity for cdk2 (IC50 value = 0.94 μM for cdk4 and >2.3 μM for other cdks). Induces cell-cycle arrest at the G2-M phase. Potentiates the apoptotic effect of taxol (Cat. No. 1097) in HeLa cells; down-regulates the antiapoptotic protein survivin. Also potently inhibits aurora kinases (IC50 values are 0.035 and 0.067 μM for aurora kinase B and A, respectively). Purity 99%. MW (observed): 422.52 |
|---|
| Size | 50 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 4-[[6-(Cyclohexylmethoxy)-1H-purin-2-yl]amino]-N,N-diethylbenzamide |
|---|
| Gene, Accession, CAS # | CAS: 444723-13-1 |
|---|
| Catalog # | 3301/50 |
|---|
| Price | |
|---|
| Order / More Info | NU 6140 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 26882548, 27496804, 29170395 |
|---|
| 產(chǎn)品資料 |
|
|