| 產(chǎn)品詳情 |
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| Product Name | LB 42708 |
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| Description | Selective inhibitor of farnesyltransferase (FTase). Blocks farnesylation of H-Ras, N-Ras and K-Ras4B (IC50 values are 0.8, 1.2 and 2.0 nM respectively). Displays >50,000-fold selectivity for FTase over geranylgeranyltransferase (GGTase) I. Inhibits VEGF-induced Ras activation; suppresses angiogenesis in vivo and in vitro (IC50 = 75 nM). Orally active. Purity 98%. MW (observed): 555.46 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [1-[[1-[(4-Bromophenyl)methyl]-1H-imidazol-5-yl]methyl]-4-(1-naphthalenyl)-1H-pyrrol-3-yl]-4-morpholinylmethanone |
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| Gene, Accession, CAS # | CAS: 226929-39-1 |
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| Catalog # | 4294/50 |
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| Price | |
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| Order / More Info | LB 42708 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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