| 產(chǎn)品詳情 |
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| Product Name | SIRT2 Inhibitor Screening Assay Kit (Fluorometric) |
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| Description | Sirtuin or Sir2 proteins are a class of proteins that possess either histone deacetylase or mono-ribosyltransferase activity. Sirtuins have been implicated in influencing aging and regulating transcription, apoptosis and stress resistance, as well as energy efficiency and alertness during low-calorie situations. Unlike other known protein deacetylases, which simply hydrolyze acetyl-lysine residues, the sirtuin-mediated deacetylation reaction couples lysine deacetylation to NAD hydrolysis. This hydrolysis yields O-acetyl-ADP-ribose, the deacetylated substrate and nicotinamide, itself an inhibitor of sirtuin activity. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase act |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Sirtuin 2 Inhibitor Screening Assay Kit, SIR2-like protein 2 Inhibitor Screening Assay Kit, NAD-dependent protein deacetylase sirtuin-2 Inhibitor Screening Assay Kit |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | K322-100 |
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| Order / More Info | SIRT2 Inhibitor Screening Assay Kit (Fluorometric) from BIOVISION, INC. |
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| Product Specific References | n/a |
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