| 產(chǎn)品詳情 |
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| Product Name | Human IgG SPARCL Assay |
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| Description | Pharmacokinetic characterization of human monoclonal IgGantibodies requires measurement of human IgG in serum of speciesused in preclinical research. This kit allows measurement of humanIgG1-4 subclasses1 in serum of mice, rats, dogs, cynomolgusmonkeys and rhesus monkeys. SPARCL? (Spatial Proximity Analyte Reagent Capture Luminescence) assays use two specific antibodies; one conjugated to HRP, the other to acridan, a chemiluminescent substrate. When HRP and acridan conjugated antibodies bind to their target biomarker they are brought into close proximity. Upon addition of hydrogen peroxide (trigger solution), HRP catalyzes oxidation of proximal acridan molecules causing a flash of chemiluminescence that is proportional to biomarker concentration. Acridan molecules distant from HRP are not oxidized and therefore produce no luminescence. This principle allows development of a range of rapid and sensitive homogeneous immunoassays. |
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| Size | 96 well plate |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | kit, assay, immunoassay, EIA |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | IGG-SP-20 |
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| Order / More Info | Human IgG SPARCL Assay from LIFE DIAGNOSTICS INC. |
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| Product Specific References | n/a |
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