| 產(chǎn)品詳情 |
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| Product Name | SC 514 |
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| Description | Orally active, ATP-competitive IKKβ inhibitor (IC50 = 3 - 12 μM) that displays > 10-fold selectivity over 28 other kinases including JNK, p38, MK2 and ERK. Attenuates NF-κB-induced gene expression of IL-6, IL-8 and COX-2 in synovial fibroblasts (IC50 values are 20, 20 and 8 μM respectively). Reduces iNOS induction and exhibits anti-inflammatory activity in vivo. Purity 98%. MW (observed): 224.3 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-Amino-[2',3'-bithiophene]-5-carboxamide |
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| Gene, Accession, CAS # | CAS: 354812-17-2 |
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| Catalog # | 3318/50 |
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| Price | |
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| Order / More Info | SC 514 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 25385442, 26331681 |
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| 產(chǎn)品資料 |
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