| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | Contactin 1 (CNTN1) (N-Term) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, rat, mouse |
|---|
| Isotype | n/a |
|---|
| Format | serum |
|---|
| Size | 100 μL |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Function:Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth.Subunit: Monomer. Interacts with CNTNAP1 in cis form. Binds to the carbonic-anhydrase like domain of protein-tyrosine phosphatase zeta. Interacts with NOTCH1 and TNR.Subcellular location: Cell membrane, Lipid-anchor, GPI-anchor.Miscellaneous: F3 shares with L1, N-CAM, MAG, and other cell adhesion molecules from nervous tissue the L2/HNK-1 carbohydrate epitope.Tissue specificity: Strongly expressed in brain and in neuroblastoma and retinoblastoma cell lines. Lower levels of expression in lung, pancreas, kidney and skeletal muscle. Also known as: Neural cell surface protein F3, F3cam,Contactin 1, CNTN1, Glycoprotein gp135. |
|---|
| Immunogen | A synthetic peptide from n-terminal region of mature human Contactin-1 conjugated to an immunogenic carrier protein was used as the antigen. |
|---|
| Other Names | F3/F11|cntn-A|CNTN1|F3|GP135|AW495098|CNTN|F3cam|F11 |
|---|
| Gene, Accession # | Gene ID: 1272,12805,117258 |
|---|
| Catalog # | ABIN571817 |
|---|
| Price | |
|---|
| Order / More Info | Contactin 1 (CNTN1) (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|