| 產(chǎn)品詳情 |
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| Product Name | TPMT, 1-245aa, Human, E.coli |
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| Description | Purity: > 95% by SDS - PAGE Format: In 20mM Tris 8.0, 0.2mM PMSF, 2mM EDTA . TPMT, thiopurine S-methyltransferase, is a cytosolic enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine and azathioprine are used as chemotherapeutic agents. TPMT activity exhibits autosomal codominant genetic polymorphism, and patients inheriting TPMT-deficiency are at high risk of potentially fatal hematopoietic toxicity. Recombinant human TPMT was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Thiopurine S-methyltransferase, Thiopurine S-methyltransferase, TPMT, Thiopurine S-methyltransferase HGNC:12014, S adenosyl L methionine thiopurine S methyltransferase, Thiopurine methyltransferase, Thiopurine S methyltransferase. |
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| Gene, Accession, CAS # | AAH05339 |
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| Catalog # | TPM0701 |
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| Price | |
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| Order / More Info | TPMT, 1-245aa, Human, E.coli from ATGen |
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| Product Specific References | n/a |
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