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| Antigenic Specificity | Rb1 |
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| Clone | 1F8 |
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| Host Species | Mouse |
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| Reactive Species | mouse, human |
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| Isotype | IgG1 |
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| Format | fluorescein (FITC) conjugate |
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| Size | 50ul |
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| Concentration | 1mg/ml |
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| Applications | ICC/IF, IHC-Fr |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse anti Rb1 [1F8]: Fluorescein. This antibody recognises retinoblastoma-associated protein (RB), a 105kDa tumour suppressor which is also known as Rb1. Rb1 functions as a transcription factor that controls cell cycle progression (at the G1/S phase transition) through its repression of E2F-mediated transcription. Mutation of the Rb gene is found frequently in human sarcomas, lung, bladder and breast carcinomas and is the molecular basis for hereditary disposition to retinoblastoma. |
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| Immunogen | Rb-b-galactosidase fusion protein spanning nucleotides 1126-1973 of human Rb gel purified from bacterial lysates |
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| Other Names | OSRC; p105-Rb; pp110; pRb; Rb; RB1; retinoblastoma 1; retinoblastoma suspectibility protein; Retinoblastoma-associated protein |
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| Gene, Accession # | n/a |
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| Catalog # | IQ610FITC |
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| Price | |
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| Order / More Info | Rb1 Antibody from IMMUQUEST LTD. |
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| Product Specific References | BA rtek J, et al. Cellular localization and T antigen binding of the retinoblastoma protein. Oncogene.1992.7(1):101-8. PMID:1741157 http://www.ncbi.nlm.nih.gov/pubmed/1741157 |
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