| 產(chǎn)品詳情 |
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| Product Name | TMI 1 |
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| Description | Adam 17 (TACE) and MMP inhibitor (IC50 values are 3, 4.7, 6.6, 8.4, 12, 26 and 26 nM for MMP-13, MMP-2, MMP-1, ADAM 17, MMP-9, MMP-7 and MMP-14, respectively). Suppresses TNF-α production in an acute LPS-mouse model. Reduces severity score in an in vivo model of rheumatoid arthritis. Displays selective cytotoxicity to tumor cells and cancer stem cells in vitro. Induces tumor apoptosis in a breast cancer in vivo model. Orally bioavailable. Purity 98%. MW (observed): 398.49 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (3S)-4-[[4-(2-Butyn-1-yloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-3-thiomorpholinecarboxamide |
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| Gene, Accession, CAS # | CAS: 287403-39-8 |
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| Catalog # | 5960/10 |
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| Price | |
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| Order / More Info | TMI 1 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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