| 產(chǎn)品詳情 |
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| Product Name | Dorsomorphin |
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| Description | Cell-permeable. A potent, selective , reversible and ATP-competitive inhibitor of AMP-activated protein kinase (AMPK) (Ki = 109 nM in the presence of 5 μM ATP and no AMP). Does not affect the activity on several structurally related kinases including JAK3, PKA, PKCθ, SYK and ZAPK. Also inhibits bone morphogenic protein (BMP) type I receptors (ALK2, ALK3 and ALK6). In addition, recently Dorsomorphin has shown to induce protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway. MW: 399.49. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-[4-(2-Piperidin-1-yl)-ethoxy)-phenyl)]-3-pyridin-4-yl- pyrazolo[1,5-a]-pyrimidine; Compound C |
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| Gene, Accession, CAS # | CAS: 866405-64-3 |
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| Catalog # | 1686-5 |
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| Order / More Info | Dorsomorphin from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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