| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | Asc (Tyr-144), phospho-specific |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, rat, mouse |
|---|
| Isotype | n/a |
|---|
| Format | affinity purified |
|---|
| Size | 100 μl |
|---|
| Concentration | n/a |
|---|
| Applications | WB, ELISA, ICC |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | This antibody was cross-adsorbed to unphosphorylated Asc (Tyr-144) peptide before affinity purification using phospho-Asc (Tyr-144) peptide (without carrier). The antibody detects phosphorylated Asc (Tyr-144) in the inflammasome. In J774 macrophage cells primed with LPS and treated with nigericin, the antibody colocalized with an inflammasome marker, caspase-1 inhibitor (FAM-YVAD-FMK). In addition, the antibody detects a 20 kDa Asc protein in western blots of J774A.1 mouse macrophages treated with pervanadate. |
|---|
| Immunogen | Asc (Tyr-144) phospho-peptide (coupled to KLH) corresponding to amino acid residues surrounding Tyr-144 in mouse Asc. This peptide sequence is highly conserved in human and rat Asc. |
|---|
| Other Names | Caspase, PYCARD, AIM, ASC, CARD5, TMS1 |
|---|
| Gene, Accession # | Q9EPB4 |
|---|
| Catalog # | AP5631 |
|---|
| Price | |
|---|
| Order / More Info | Asc (Tyr-144), phospho-specific Antibody from ECM BIOSCIENCES LLC |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|