| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD40L/CD154 |
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| Clone | LL2 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100μg/50μg |
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| Concentration | n/a |
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| Applications | Flow cytometry, IF, T cell activation, block CD40-CD40L interaction, ELISA for sCD154 detection |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD40 ligand also known as TRAP, gp39, TNFSF5, is a 261 amino acid type II transmembrane glycoprotein belonging to the TNF superfamily. CD40 ligand is expressed predominantly on activated CD4+ T cells and is also found on other cell types, including NK cells, mast cells, basophils and eosinophils. Genetic alterations in the CD40L results in the absence of a functional molecule on activated T cells and are responsible for the occurrence of X-linked hyper-IgM syndrome. LL48 clone is a CD40L neutralizing antibody and plays an important role in costimulatory interactions between T and B lymphocytes, and antigen-presenting cells and lymphocytes regulating the immune system at multiple levels. (Tong AW et al, 2001; Clin. Canc. Res., 7:691-703; Hill A. et al, 1993; Nature, 361:494-503; Peguet-Navarro J. et al, 1995; J. Immunol., 155:4241-4247) |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | DDX0141 |
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| Price | |
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| Order / More Info | CD40L/CD154 Antibody from DENDRITICS SAS |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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