| 產(chǎn)品詳情 |
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| Product Name | NBI 35965 hydrochloride |
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| Description | Potent and selective corticotropin-releasing factor receptor 1 (CRF1) antagonist (Ki values are 4 and > 10000 nM at CRF1 and CRF2 respectively). Inhibits cAMP accumulation and adrenocorticotropic hormone (ACTH) production in vitro (pIC50 values are 7.1 and 6.9 respectively) and attenuates CRF and ACTH production in vivo. Orally active and brain penetrant with anxiolytic activity. Purity 98%. MW (observed): 437.79 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (7S)-6-(Cyclopropylmethyl)-2-(2,4-dichlorophenyl)-7-ethyl-7,8-dihydro-4-methyl-6H-1,3,6,8a-tetraazaacenaphthylene hydrochloride |
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| Gene, Accession, CAS # | CAS: 1782228-59-4 |
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| Catalog # | 3100/50 |
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| Price | |
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| Order / More Info | NBI 35965 hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 23624287 |
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| 產(chǎn)品資料 |
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