| 產(chǎn)品詳情 |
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| Product Name | (+/-)-NBI 74330 |
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| Description | Potent and selective CXCR3 antagonist; potently inhibits 125I-CXCL10 binding to CXCR3 (pKi = 8.13). Inhibits calcium mobilization in response to CXCL11 and CXCL10 in RBL cells. Exhibits no significant effect on chemotaxis induced by CXCR4 or CCR7. Displays a five-fold greater affinity for CXCR3 than (±)-AMG 487. This product is racemic. . Purity 98%. MW (observed): 605.58 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-1-[(3-4(-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)benzeneacetamide |
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| Gene, Accession, CAS # | CAS: 473722-68-8 |
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| Catalog # | 4528/10 |
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| Price | |
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| Order / More Info | (+/-)-NBI 74330 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 30076959 |
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| 產(chǎn)品資料 |
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