| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | CD46 |
|---|
| Clone | monoclonal |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG2a, k |
|---|
| Format | purified |
|---|
| Size | 100ul, 50ul |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA, WB, Flow cytometry, ICC/IF, IHC |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Membrane Cofactor Protein (CD46) is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 regulates the complement cascade by inhibiting C3b and C4b deposited on self tissue. This protein is a cofactor that binds to C3b and C4b, allowing their degradation by a plasma serine protease called factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is implicated in the development and/or progression of selected cancer types. |
|---|
| Immunogen | Recombinant human CD46 (35-313aa) purified from E. coli |
|---|
| Other Names | Membrane cofactor protein isoform 14, AHuS2, MCP, MIC10, TLX, TRA2.10 |
|---|
| Gene, Accession # | NP 758860 |
|---|
| Catalog # | ATGA0326 |
|---|
| Price | |
|---|
| Order / More Info | CD46 Antibody from ATGen |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|