| 產(chǎn)品詳情 |
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| Product Name | Hpd, 1-393aa, Mouse, His-tag, E.coli |
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| Description | Purity: > 90% by SDS-PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol. Hpd, also known as 4-hydroxyphenylpyruvate dioxygenase, is a Fe-containing enzyme that catalyzes the second reaction in the catabolism of tyrosine the conversion of 4-hydroxyphenylpyruvate to homogentisate. Existing as a homodimer, Hpd uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. Defects in the gene encoding Hpd are the cause of tyrosinemia type 3 and hawkinsinuria, both of which are inborn errors of metabolism that are associated with a variety of symptoms, including mental retardation and seizures and hair and urine abnormalities. Recombinant mouse Hpd protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 50ug, 10ug, |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | 4-hydroxyphenylpyruvate dioxygenase, 4HPPD, Fla, Flp, Hppd, Laf |
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| Gene, Accession, CAS # | NP 032303 |
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| Catalog # | ATGP3760 |
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| Price | |
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| Order / More Info | Hpd, 1-393aa, Mouse, His-tag, E.coli from ATGen |
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| Product Specific References | n/a |
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