| 產(chǎn)品詳情 |
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| Antigenic Specificity | COMT |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 μl, 100 μl, 200 μl |
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| Concentration | > 1 mg/ml |
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| Applications | WB, IHC, IF/ICC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | COMT Antibody is a Rabbit Polyclonal antibody against COMT. Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. |
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| Immunogen | Recombinant protein of human COMT. |
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| Other Names | Catechol O methyltransferase; COMT; Catechol O-methyltransferase; membrane-bound form; catechol-O-methyltransferase; MB-COMT; S-COMT; OTTHUMP00000197749; OTTHUMP00000197750; HEL-S-98n |
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| Gene, Accession # | COMT, Gene ID: 1312, SwissProt: P21964 |
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| Catalog # | abx004737 |
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| Price | |
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| Order / More Info | COMT Antibody from ABBEXA |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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