| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | CD200 |
|---|
| Clone | OX-2 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | rat |
|---|
| Isotype | IgG1, κ |
|---|
| Format | phycoerythrin (PE) conjugate |
|---|
| Size | 100 μg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry (FC) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | PE anti-rat CD200. CD200, known as OX-2, is a type I membrane glycoprotein member of the Ig supergene family. CD200 is expressed on B cells, a subset of T cells, thymocytes, follicular dendritic cells, neurons, keratinocytes, vascular endothelium, and some smooth muscle. The interaction of CD200 with CD200 receptor provide a potent costimulatory T-cell signal in the presence of TCR signaling, stimulate macrophages, and inhibit mast cell degranulation. It was reported that increased expression of OX-2 on DC was associated with inhibition of cytokine production and renal allograft rejection. Incubation of lymphocytes with OX-2 Fc inhibits a primary mixed lymphocyte reaction in vitro, decreased IL-2 and IFN-γ production, increased IL-4 and IL-10 production. In vivo infusion of OX-2 Fc promotes both skin and renal graft survival and decreases the antibody response. The OX-2 antibody reacts with rat OX-2 antigen. |
|---|
| Immunogen | n/a |
|---|
| Other Names | OX-2 antigen, MRC |
|---|
| Gene, Accession # | Gene ID: 24560 |
|---|
| Catalog # | 204807 |
|---|
| Price | |
|---|
| Order / More Info | CD200 Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|