| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | 2-Deoxy-D-Glucose |
|---|
| Description | 2-Deoxy-D-Glucose is a glucose analog that has long been known to act as a competitive inhibitor of glucose metabolism. Upon transport into the cells, 2-DG is phosphorylated by hexokinase to 2-DG-P. However, unlike G-6-P, 2-DG-P cannot be further metabolized by phosphohexose isomerase, which converts G-6-P to fructose-6-phosphate. 2-Deoxyglucose-P is trapped and accumulated in the cells, leading to inhibition of glycolysis mainly at the step of phosphorylation of glucose by hexokinase. Inhibition of this rate-limiting step by 2-DG causes a depletion of cellular ATP, leading to blockage of cell cycle progression and cell death in vitro. MW: 164.16. Purity ≥98% GC |
|---|
| Size | 100 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 2-Deoxy-D-arabinohexose, 2-Deoxyglucose |
|---|
| Gene, Accession, CAS # | CAS: 154-17-6 |
|---|
| Catalog # | B1048-100 |
|---|
| Price | |
|---|
| Order / More Info | 2-Deoxy-D-Glucose from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|