| 產(chǎn)品詳情 |
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| Product Name | GSK-199 hydrochloride |
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| Description | GSK-199 is a potent, reversible inhibitor of PAD4 (IC50 = 200 nM. It binds to the low-calcium form of the enzyme and is selective for PAD4 over PAD1-3. It is less potent than the related PAD4 inhibitor GSK484 (IC50 = 50 nM). GSK-199 can inhibit the citrullination of PAD4 target proteins and diminish the formation of neutrophil extracellular traps in mouse neutrophils. MW: 468.98. Purity ≥98% |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (R)-(3-Aminopiperidin-1-yl)(2-(1-ethyl-1H-pyrrolo[2,3-b]pyridin-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride |
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| Gene, Accession, CAS # | CAS: 1549811-53-1 |
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| Catalog # | B1037-1000 |
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| Order / More Info | GSK-199 hydrochloride from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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