| 產(chǎn)品詳情 |
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| Product Name | KU-0060648 |
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| Description | KU-0060648 is a potent and selective inhibitor of DNA-dependent protein kinase (DNA-PK), (IC50 = 8.6 nM). Displays 20-1000 fold selectivity for DNA-PK over other PIKKs and a panel of 60 kinases. Inhibits proliferation of MCF7 cells in vitro and delays growth of MCF7 xenografts in mice. Also enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency, and attenuates nonhomologous end-joining (NHEJ). MW: 582.71. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-Ethyl-N-[4-[2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-8-yl]-1-dibenzothienyl]-1-piperazineacetamide |
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| Gene, Accession, CAS # | CAS: 881375-00-4 |
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| Catalog # | B1115-5 |
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| Price | |
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| Order / More Info | KU-0060648 from BIOVISION, INC. |
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| Product Specific References | n/a |
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