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| Antigenic Specificity | TRADD |
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| Clone | T.661.2 |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 μL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 1:50, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TRADD Monoclonal Antibody (T.661.2). The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. |
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| Immunogen | n/a |
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| Other Names | TNFR1-associated death domain protein; tumor necrosis factor receptor type 1 associated death domain protein; tumor necrosis factor receptor type 1-associated DEATH domain protein; tumor necrosis factor receptor-1-associated protein |
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| Gene, Accession # | Entrez: 8717; Uniprot: Q15628 |
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| Catalog # | MA5-15063 |
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| Price | |
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| Order / More Info | TRADD Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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