| 產(chǎn)品詳情 |
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| Product Name | JZL 184 |
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| Description | Potent and selective MAGL inhibitor. Blocks hydrolysis of the endocannabinoid 2-arachidonyl glycerol (2-AG) in vivo in the mouse brain (IC50 = 8 nM). Potentiates depolarization-induced suppression of excitability in cerebellar Purkinje neurons. Exhibits >300-fold selectivity for MAGL over FAAH in vitro. Attenuates nociception in neuropathic and inflammatory pain models. Also reduces free fatty acid levels in primary tumors. Purity 98%. MW (observed): 520.49 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[Bis(1,3-benzodioxol-5-yl)hydroxymethyl]-1-piperidinecarboxylic acid 4-nitrophenyl ester |
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| Gene, Accession, CAS # | CAS: 1101854-58-3 |
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| Catalog # | 3836/10 |
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| Price | |
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| Order / More Info | JZL 184 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 24089517, 24136226, 24803745, 25684407, 26648844 |
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| 產(chǎn)品資料 |
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