| 產(chǎn)品詳情 |
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| Product Name | JQEZ5 |
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| Description | Potent and selective SAM-competitive EZH2 lysine methyltransferase inhibitor (IC50 = 11 nM). Selectively binds EZH2 over a panel of 22 methyltransferases. Reduces global level of the PRC2-associated mark H3K27me3 in K562 cells. Suppresses cell growth in CML cells. Inhibits colony formation of primary human CD34+ CML stem/ progenitor cells. Antitumor effects in vivo. Purity 98%. MW (observed): 542.69 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-pyrazolo[3,4-b]pyridine-4-carboxamide |
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| Gene, Accession, CAS # | CAS: 1913252-04-6 |
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| Catalog # | 6153/10 |
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| Price | |
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| Order / More Info | JQEZ5 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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