| 產(chǎn)品詳情 |
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| Product Name | JNJ 10191584 maleate |
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| Description | Highly selective histamine H4 receptor silent antagonist; binds with high affinity to the human H4 receptor (Ki = 26 nM). > 540-fold selective over the H3 receptor (Ki = 14.1 μM). Inhibits mast cell and eosinophil chemotaxis in vitro with IC50 values of 138 and 530 nM respectively. Orally active in vivo. Purity 99%. MW (observed): 394.81 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-[(5-Chloro-1H-benzimidazol-2-yl)carbonyl]-4-methylpiperazine maleate. VUF 6002 |
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| Gene, Accession, CAS # | CAS: 869497-75-6 |
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| Catalog # | 2441/50 |
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| Order / More Info | JNJ 10191584 maleate from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 19413571, 22624822, 27773822 |
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