| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | Acyl-CoA Synthetase Fluorometric Assay Kit |
|---|
| Description | Acyl-CoA Synthetase (ACS) also known as Acyl-CoA ligase, is a ubiquitous enzyme that catalyzes the reaction of free fatty acids and Coenzyme A (CoA) to generate Fatty Acyl-CoAs through an ATP-dependent mechanism. The incorporation of this CoA moiety generates a thio-ester bond that effectively activates the fatty acid for downstream biological processes. Unlike their fatty acid counterparts, Fatty acyl-CoAs also serve as precursors of cellular lipids. Dysregulation of the various isoforms of ACS have been implicated in a number of metabolic diseases, including Non-Alcoholic Fatty Liver Disease (NAFLD) and Hepatic Fibrosis. ACS also plays a role in regulating apoptosis. BioVision's Acyl-CoA Synthetase Fluorometric assay kit provides a rapid, sensitive and straightforward way to measure ACS activity in various samples. In the assay, acyl-CoA produced by ACS activity is metabolized by the Enzyme Mix, Developer Mix and Converter Mix to generate an intermediate compound, which reacts with a probe, yielding a fluorescent signal that can be measured with excitation at 535 nm and emission at 587 nm. This assay can detect ACS activity as low as 5 mU/μl in samples. |
|---|
| Size | 100 assays |
|---|
| Concentration | n/a |
|---|
| Applications | Measurement of Acyl-CoA Synthetase activity in various tissues/cells |
|---|
| Other Names | Acyl-CoA Synthetase Assay Kit, ACS, Acyl-CoA Synthetase Fluorometric Assay Kit, Acyl-CoA Synthetase Fluorometric Assay, Acyl-CoA Synthetase Fluorometric Kit, ACS Fluorometric Assay, Acyl-CoA Synthetase Kit, ACS Fluorometric Kit, ACS Fluorometric Assay Kit |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | K184-100 |
|---|
| Price | |
|---|
| Order / More Info | Acyl-CoA Synthetase Fluorometric Assay Kit from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|