| 產(chǎn)品詳情 |
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| Antigenic Specificity | PDCD1 / CD279 / PD-1 |
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| Clone | monoclonal |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a |
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| Format | Protein G purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | Flo (1:10 - 1:25), IHC, IHC-Fr |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PDCD1 / CD279 / PD-1 Antibody LS-C44900. Recognizes mouse CD279, a 55kD cell surface protein which is a member of the CD28/CTLA-4 family, otherwise known as programmed death-1 (PD-1). CD279 is expressed predominantly on activated T- and B- lymphocytes and on a subset of thymocytes. Studies suggest that CD279, an immunoinhibitory receptor, plays a critical role in peripheral tolerance induction and prevention of autoimmune disease. Two members of the B7 family, B7-H1 (PD-L1) and B7-DC (PD-L2), have been identified as the ligands for CD279. Antibodies produced by clone RMP1-14 have been reported to block the binding of both B7-H1-Ig and B7-DC-Ig fusion proteins to PD-1 transfected BHK cells(1). |
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| Immunogen | PD-1 transfected BHK cells. |
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| Other Names | PDCD1, CD279, HPD-1, HPD-l, PD1, Protein PD-1, SLEB2, PD-1, CD279 antigen, Programmed cell death 1 |
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| Gene, Accession # | PDCD1, Gene ID: 5133 |
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| Catalog # | LS-C44900 |
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| Price | |
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| Order / More Info | PDCD1 / CD279 / PD-1 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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