| 產(chǎn)品詳情 |
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| Antigenic Specificity | Blimp-1 |
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| Clone | ROS195G |
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| Host Species | Mouse |
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| Reactive Species | human, cross-reactivity: mouse |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Western Blot (WB), IHC, IP, Immunofluorescence Microscopy (IF), ELISA |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-Blimp-1. Blimp-1 is a 98 Kd protein containing five Kuppel-type zinc finger domains that confer sequence specific DNA binding.? It has been postulated to be a master regulator of terminal B cell differentiation. In the BCL-1 lymphoma model of differentiation from mature B cells to plasma cells, ectopic expression of Blimp-1 is sufficient to cause terminal differentiation manifested by loss of surface immunoglobulin, IgM secretion, expression of syndecan-1 and cessation of cell division. Recently, it is reported that Blimp-1 is also involved in T cell differentiation and T cell homeostasis and suppression of IL-2 production. |
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| Immunogen | Recombinant GST-blimp-1 protein |
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| Other Names | B lymphocyte-induced maturation protein-1, PRDM-1, BLIMP1 |
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| Gene, Accession # | Gene ID: 639 |
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| Catalog # | 648202 |
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| Price | |
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| Order / More Info | Blimp-1 Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 22510872,24019486 |
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| 產(chǎn)品資料 |
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