| 產(chǎn)品詳情 |
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| Product Name | (+/-)-AMG 487 |
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| Description | Antagonist of CXCR3; inhibits binding of 125I-IP-10 and 125I-ITAC to CXCR3 (IC50 values are 8.0 and 8.2 nM respectively). Inhibits CXCR3-mediated cell migration by the chemokines IP-10, ITAC and MiG in vitro (IC50 values are 8, 15 and 36 nM respectively). Also shown to inhibit lung metastasis in a mouse model of metastatic breast cancer. This product is racemic. . Purity 98%. MW (observed): 603.59 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-1-[(3-4(-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)benzeneacetamide |
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| Gene, Accession, CAS # | CAS: 947536-03-0 |
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| Catalog # | 4487/50 |
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| Price | |
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| Order / More Info | (+/-)-AMG 487 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 28986561, 30359318 |
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| 產(chǎn)品資料 |
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