| 產(chǎn)品詳情 |
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| Antigenic Specificity | Sortilin |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 μL |
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| Concentration | lyophilized |
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| Applications | ELISA: 1:5,000, Immunohistochemistry: 1:1,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Sortilin Polyclonal Antibody. Sortilin functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Sortilin is required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). It is also required for protein transport from the Golgi apparatus to the endosomes. Sortilin promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also, Sortilin acts as a receptor for neurotensin. |
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| Immunogen | n/a |
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| Other Names | neurotensin receptor 3 |
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| Gene, Accession # | Entrez: 20661, 6272, 83576; Uniprot: O54861, Q6PHU5, Q99523 |
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| Catalog # | PA1-18312 |
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| Price | |
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| Order / More Info | Sortilin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 29100377 |
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| 產(chǎn)品資料 |
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