| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | CGP 57380 |
|---|
| Description | Inhibitor of MAP-kinase interacting kinase-1 (Mnk1, MKNK1) (IC50 = 2.2 μM) that displays selectivity over p38, JNK1, ERK1, ERK2, PKC and c-src family kinases. Blocks phosphorylation of eIF4E in cellular assays (IC50 = 3 μM) and inhibits LPS-induced TNFα expression in macrophages. Purity 98%. MW (observed): 244.23 |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | N3-(4-Fluorophenyl)-1H-pyrazolo-[3,4-d]pyrimidine-3,4-diamine |
|---|
| Gene, Accession, CAS # | CAS: 522629-08-9 |
|---|
| Catalog # | 2731/10 |
|---|
| Price | |
|---|
| Order / More Info | CGP 57380 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 21068317, 22070140, 24047601, 25187540, 25561727, 27626179, 28178522 |
|---|
| 產(chǎn)品資料 |
|
|