| 產(chǎn)品詳情 |
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| Antigenic Specificity | BACE2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 μL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BACE2 Polyclonal Antibody. BACE2 or Beta Secretase 2 is responsible for the proteolytic processing of the amyloid precursor protein (APP). BACE2 cleaves APP between residues 690 and 691. This cleavage leads to the generation and extracellular release of beta-cleaved soluble APP. BACE2 is also know to cleave APP between residues 671 and 672. Accumulation of APP is a signature of Alzheimer disease and frequent complication of adult Down syndrome patients. |
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| Immunogen | n/a |
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| Other Names | AEPLC, ALP56, ASP1, ASP21, BAE2, CEAP1, DRAP, 56 kDa aspartic-like protease, Down syndrome region aspartic protease, asp 1, aspartic-like protease 56 kDa, aspartyl protease 1, beta secretase 2, beta-secretase 2, beta-site APP cleaving enzyme 2, beta-site amyloid beta A4 precursor protein-cleaving enzyme 2, be |
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| Gene, Accession # | Entrez: 25825, 288227; Uniprot: Q6IE75, Q9Y5Z0 |
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| Catalog # | PA5-29882 |
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| Price | |
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| Order / More Info | BACE2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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