| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | CD20 (human) |
|---|
| Clone | CAT13.6E12 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG2a |
|---|
| Format | purified |
|---|
| Size | 100 ug |
|---|
| Concentration | n/a |
|---|
| Applications | IHC, FACS |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Intermediate differentiation stage B-cell marker. Monoclonal antibody CAT13.6E12 recognizes the CD20 antigen. CD20 belongs to the MS4A family (membrane-spanning 4-domains subfamily A). Its expression is restricted to normal and neoplastic B-cells. It is expressed by pre-B-cells in the bone marrow, and expression persists during B-cell maturation but is lost upon terminal differentiation into plasma cells. CD20 is not glycosylated. CD20 is not phosphorylated in resting B-cells, but becomes heavily phosphorylated after mitogen stimulation. Three cell surface isoforms 33, 35 and 37kD, result from differential phosphorylation of a single core 33kD protein within the cytoplasmic domain. Multiple proteins are coimmunoprecipitated with CD20, suggesting that it may be a component of a multimeric surface receptor complex. Monoclonal antibodies against CD20 are used therapeutically, such as Rituximab (Mabthera) or Britumomab (Zevalin). Application: IHC (f), FACS |
|---|
| Immunogen | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession # | n/a |
|---|
| Catalog # | T-1371.0100 |
|---|
| Price | |
|---|
| Order / More Info | CD20 (human) Antibody from PENINSULA LABORATORIES INTERNATIONAL, INC.
|
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|