| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | TIM3 |
|---|
| Clone | 25F.1D6 |
|---|
| Host Species | Rat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG2a, kappa |
|---|
| Format | fluorescein (FITC) conjugate |
|---|
| Size | 100 ug |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 1 μg /1x10^6 cells, Immunohistochemistry: Assay Dependent |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | TIM3 Monoclonal Antibody (25F.1D6), FITC. TIM3 (Hepatitis A virus cellular receptor 2, HAVCR2, T-cell immunoglobulin, mucin-dmain containing-3) is a 281 amino acid long, Type-1 Th1- specific cell surface glycoprotein expressed on terminally differentiated CD4+Th1 and CD8+Tc1 cells. TIM3 consists of an IgV-like domain, a mucin-like domain in the extracellular region, and a conserved Tyrosine phosphorylation motif in the cytoplasmic region. TIM3 is involved in macrophage activation and induction of autoimmune diseases. Further, TIM3 down-regulates aggressive Th1-mediated immune responses and facilitates in the development of immune tolerance. Pathological significance of TIM3 has been attributed to Experimental autoimmune encephalomyelitis (E |
|---|
| Immunogen | n/a |
|---|
| Other Names | HAVCR2, hepatitis A virus cellular receptor 2, FLJ14428, KIM-3, TIMD3, T cell immunoglobulin mucin 3, kidney injury molecule 5 |
|---|
| Gene, Accession # | Entrez: 171285; Uniprot: Q8VIM0 |
|---|
| Catalog # | MA5-17957 |
|---|
| Price | |
|---|
| Order / More Info | TIM3 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|