| 產(chǎn)品詳情 |
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| Product Name | A-967079 |
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| Description | MW: 207.3. A-967079 is a TRPA1 antagonist (1) and cell permeable. It has been found to be a potent blocker of TRPA1 channels. It is an oxime analogue and resembles AP18 from a structural perspective, although it has a methyl addition and a chlorine-?uorine substitution. However, compared with AP18 and HC-030031, A-967079 is signi?cantly more potent (100-fold on human and 24-fold on rat TRPA1) and has a much improved pharmacokinetic pro?le. A-967079 is also more selective, with >1000-fold selectivity over other TRP channels and >150-fold selectivity over 75 other tested proteins (2). |
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| Size | 10 mg, 50 mg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | (1E,3E)-1-(4-Fluorophenyl)-N-hydroxy-2-methyl-1-penten-3-imine |
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| Gene, Accession, CAS # | CAS: 1170613-55-4 |
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| Catalog # | abx076611 |
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| Order / More Info | A-967079 from ABBEXA |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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