| 產(chǎn)品詳情 |
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| Product Name | EP2 Receptor (human) Reporter Assay Kit |
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| Description | PGE2 is one of the most important biologically active prostanoids which exerts its actions mainly by binding to four distinct E-type prostanoid receptors: EP1, EP2, EP3, and EP4. These four GPCRs exhibit differences in signal transduction mechanisms, tissue localization, and regulation of expression. EP2 receptors are expressed in many tissues and cells to mediate various PGE2 actions. The receptors couple to Gs to stimulate the cAMP second messenger signal transduction pathway. EP2 receptors play important roles in mucosal protection, gastrointestinal secretion, and motility. The diverse effects of PGE2 acting via EP2 receptors make it an interesting drug target. Therefore, EP2 subtype selective agonists, antagonists, and modulators have been identified with potential therapeutic applications. |
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| Size | 96 well |
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| Concentration | n/a |
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| Applications | Cell-Based Assay, Chemiluminescence, High-Throughput Screening, Reverse Transfection Reporter Assay |
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| Other Names | PGE2 Receptor 2|Prostaglandin E2 Receptor 2 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 601380-96WELLS |
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| Order / More Info | EP2 Receptor (human) Reporter Assay Kit from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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