| 產(chǎn)品詳情 |
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| Product Name | AZD-6482 |
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| Description | AZD-6482 is a potent and selective inhibitor of PI 3-kinase β (PI 3-Kβ) (IC50 values are 0.69, 13.6, 47.8 and 136 nM for PI 3-Kβ, PI 3-Kδ, PI 3-Kγ and PI 3-Kα, respectively). It displays 80-fold selectivity for PI3Kβ over PI3k-C2 and DNA-PK and more than 1,000-fold over other PI3K-related kinases. AZD6482 blocks Akt signaling and tumor growth in a large number of cancer cell lines, including those that are dependent on PI3Kβ activation or PTEN loss. MW: 408.45. Purity ≥98% by HPLC |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (-)-2-[[(1R)-1-[7-Methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid |
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| Gene, Accession, CAS # | CAS: 1173900-33-8 |
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| Catalog # | B1143-25 |
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| Price | |
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| Order / More Info | AZD-6482 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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