| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | Glia Maturation Factor, beta (GMFB) protein |
|---|
| Description | Glia Maturation Factor-Beta (GMF-Beta) is a 17 kDa protein nerve gorwth factor identified as a growth and differentiation factor in the vertebrate brain.Glia Maturation Factor-Beta stimulates differentiation of normal neurons as well as glial cells. GMFB inhibits the proliferation of the N-18 neuroblastoma line and the C6 glioma line while promoting their phenotypic expression.GMF-beta inhances the phenotypic expression of glia and neurons thus inhibits the proliferation of their respective tumors when added to cell culture. Although astrocytes produce GMF-b and stores it inside the cells, they don't secrete the GMF-B into the cultured medium. Cell- surface GMFb acts on the target cells at close range when cells are in direct contact. GMF-Beta is produced by thymic epithelial cells and plays an important role in T cell development in favor of CD4+ T cells.GMF-Beta is a brain-specific protein which belongs to the actin-binding proteins (ADF) family. GMF-beta appears to play a role in the differentiation, maintenance, and regeneration of the nervous system. It also supports the progression of certain auto-immune diseases, possibly through its ability to induce the production and secretion of various pro-inflammatory cytokines Synonyms: Glia maturation factor beta, GMFB, GMF-B, GMF-beta, GMF |
|---|
| Size | 2 μg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | fc25b01|zgc:56451|zgc:86831|wu:fa97c03|wu:fc25b01|GMFB|DKFZp459J101|gmfb|GMF|3110001H22Rik|3110001O16Rik|AI851627|C79176|D14Ertd630e |
|---|
| Gene, Accession, CAS # | Gene ID: 2764 |
|---|
| Catalog # | ABIN804782 |
|---|
| Price | |
|---|
| Order / More Info | Glia Maturation Factor, beta (GMFB) protein from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|