| 產(chǎn)品詳情 |
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| Product Name | Chk2 Inhibitor |
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| Description | A cell-permeable, potent, and ATP-competitive inhibitor of Chk2 (checkpoint kinase 2; IC50 = 15 nM; Ki = 37 nM). Displays ~1,000-fold greater selectivity for Chk2 compared to Cdk1/cyclin B and CK1 (IC50 = 12 μM and 17 μM, respectively) and only weakly affects the activities of a panel of 31 kinases (< 25% inhibition at 10 μM), including Chk1. Shown to rescue both peripheral CD4+ and CD8+ T-cells from γ-irradiation-induced apoptosis with an EC50 of 3 μM and 7.6 μM, respectively. MW: 363.8. Purity ≥98% by HPLC |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide |
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| Gene, Accession, CAS # | CAS: 516480-79-8 |
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| Catalog # | 1702-1 |
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| Price | |
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| Order / More Info | Chk2 Inhibitor from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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