| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | ATM |
|---|
| Clone | 3E8 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, mouse, nonhuman primate, rat |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100 μg |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry (Paraffin): 2-10 μg/mL, Immunoprecipitation: 2-10 μg/mL, Western Blot: 1-2 μg/mL |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | ATM Monoclonal Antibody (3E8). Ataxia-telangiectasia Mutated (ATM) is a protein that belongs to the PI3/PI4 kinase family. Ataxia-telangiectasia is a rare autosomal recessive disorder characterized by progressive neurologic degeneration, immunologic deficiency, and an increased risk of lymphoid cancer. The ATM gene codes for a protein belonging to the phosphoinositide 3-kinase (PI3K) superfamily. ATM phosphorylates proteins instead of lipid and has many downstream targets that act as cell-cycle regulators including: P53, Mdm2, BRCA1, and SMC1. The ATM protein is responsible for repairing double-stranded DNA breaks that occur because of ionizing radiation and other mutagens. The ATM's C-terminal region has extensive homology to the catalytic |
|---|
| Immunogen | n/a |
|---|
| Other Names | AT complementation group A, AT complementation group C, AT complementation group D, AT complementation group E, AT mutated protein, AT1, ATA, Ataxia t |
|---|
| Gene, Accession # | Entrez: 11920, 300711, 472; Uniprot: Q13315, Q62388 |
|---|
| Catalog # | MA1-23154 |
|---|
| Price | |
|---|
| Order / More Info | ATM Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|