| 產(chǎn)品詳情 |
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| Product Name | JZL195 |
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| Description | JZL195 is a potent dual inhibitor of Monoacylglycerol lipase (MAGL) (IC50 = 2 nM) and fatty acid amide hydrolase (FAAH) (IC50 = 4 nM), enzymes that degrade the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide (AEA), the endogenous ligands for the cannabinoid G-protein coupled receptors CB1 and CB2. It poorly inhibits neuropathy target esterase and ABHD6 and does not inhibit other brain serine hydrolases. JZL 195 displays time-dependent inhibition of FAAH and MAGL in vivo, consistent with a covalent mechanism of activation. MW: 433.46. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[(3-Phenoxyphenyl)methyl]-1-piper?azinecarboxylic acid 4-nitrophenyl ester |
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| Gene, Accession, CAS # | CAS: 1210004-12-8 |
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| Catalog # | B1064-5 |
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| Order / More Info | JZL195 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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