| 產(chǎn)品詳情 |
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| Product Name | Fenobam |
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| Description | Potent and selective non-competitive mGlu5 negative allosteric modulator (NAM) that also displays inverse agonist properties; blocks mGlu5 constitutive activity in vitro (IC50 = 87 nM). Acts at an allosteric modulatory site shared with MPEP and binds the mGlu5 receptor with Kd values of 54 and 31 nM for rat and human receptors respectively. Displays anxiolytic activity following oral administration in vivo; also exhibits analgesic properties. Purity 99%. MW (observed): 266.69 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(3-Chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)urea |
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| Gene, Accession, CAS # | CAS: 57653-26-6 |
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| Catalog # | 2386/10 |
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| Price | |
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| Order / More Info | Fenobam from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 22449017 |
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| 產(chǎn)品資料 |
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