| 產(chǎn)品詳情 |
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| Antigenic Specificity | Human AMPK alpha-1 (phospho Thr172) |
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| Clone | 20I3M30 |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ICC, IF, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-Human AMPK alpha-1 (phospho Thr172) monoclonal antibody for ICC, IF, WB. AMPKa belongs to the family of AMP activated protein kinases, that plays a central role in regulating cellular and organismal energy balance in response to the balance between AMP/ATP, and intracellular Ca2+ levels. AMPK exists as a heterotrimer comprising of catalytic alpha subunit, and regulatory beta and gamma subunits. The alpha subunit is activated by increases in the cellular AMP:ATP ratio caused by metabolic stresses, and can mediate the effects of the adipokines leptin and adiponectin. Two isoforms differ in subcellular localization and AMP-dependence. Phosphorylation of threonine 172 in the alpha subunit is a key determinant of AMPK activity. |
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| Immunogen | Phosphopeptide corresponding to amino acids 168-178 of human AMPK alpha |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 5562, UniProt: Q13131 |
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| Catalog # | CABT-L1543 |
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| Price | |
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| Order / More Info | Human AMPK alpha-1 (phospho Thr172) Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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