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| Antigenic Specificity | CD45RO (CD45RO) |
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| Clone | UCHL-1 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a |
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| Format | supernatant |
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| Size | 1 mL |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FACS),Immunohistochemistry (IHC),Immunohistochemistry (Frozen Sections) (IHC (fro)),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD45 is a transmembrane tyrosine phosphatase that is present on all leukocytes. CD45 regulates the threshold of T cell antigen receptor (TCR) signaling through dephosphorylation of protein tyrosine kinases. CD45R and CD45RO are two of multiple CD45 isoforms generated by alternative splicing. CD45RO is present on 50% of T cells, most granulocytes and monocytes and most mature T cell tumours. UCH-L1 may identify abnormalities of functional T-cell subsets in immune disorders and can be used in tumour diagnosis. |
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| Immunogen | The anti-CD45RO antibody UCHL-1 is a mouse monoclonal IgG2a antibody derived by fusion of NSI mouse myeloma cells with spleen cells from a BALB/c mouse immunized with antigen isolated from the Il-2 dependent T-cell line CA-1. |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | ABIN335274 |
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| Price | |
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| Order / More Info | CD45RO (CD45RO) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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