| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | Embelin |
|---|
| Description | Cell-permeable, non-peptide inhibitor of X-linked inhibitor of apoptosis (XIAP) (IC50 = 4.1 μM in competition binding assay with Smac peptide); binds to the BIR3 domain, preventing XIAP interaction with caspase-9 and Smac. Inhibits cell growth, induces apoptosis and activates caspase-9 in prostate cancer cells (IC50 4 - 6 μM), but has a weaker effect on normal prostate cells (IC50 = 19 - 20 μM). Overcomes the protective effect of XIAP on apoptosis in XIAP-transfected Jurkat cells. Anti-tumor, analgesic and anti-inflammatory in vivo. Purity 98%. MW (observed): 294.39 |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 2,5-Dihydroxy-3-undecyl-2,5-cyclohexadiene-1,4-dione |
|---|
| Gene, Accession, CAS # | CAS: 550-24-3 |
|---|
| Catalog # | 2156/10 |
|---|
| Price | |
|---|
| Order / More Info | Embelin from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 23446637 |
|---|
| 產(chǎn)品資料 |
|
|