| 產(chǎn)品詳情 |
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| Antigenic Specificity | Human CD45 |
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| Clone | IJ41 |
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| Host Species | Mouse |
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| Reactive Species | human, chimpanzee |
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| Isotype | IgG1 |
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| Format | Alexa Fluor? 594 conjugate |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IHC-P |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse Anti-Human CD45 monoclonal antibody for IHC-P. CD45 is a 180-240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. |
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| Immunogen | CD45.Structure: Tyrosine phosphatases, type I transmembrane protein, 180-240 kD (multiple isoforms) |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 5788, UniProt: M9MML4 |
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| Catalog # | DMAB-SYL01 |
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| Price | |
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| Order / More Info | Human CD45 Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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