| 產(chǎn)品詳情 |
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| Antigenic Specificity | ALK |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | Protein A/G purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | FC, IF, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Monoclonal antibody to detect ALK in human samples. The wild-type anaplastic lymphoma kinase (ALK) protein is a 200kDa transmembrane receptor tyrosine kinase. Its expression is restricted to a few scattered cells in the nervous system (some glial cells and neurons, and a few endothelial cells and pericytes. The hybrid gene, NPM-ALK, created by the t(2;5)(p23;q35) chromosomal translocation encodes part of the nucleolar phosphoprotein, nucleophosmin (NPM), joined to the entire cytoplasmic portion of the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase. As a consequence, the ALK gene comes under the control of the NPM promoter, which induces a permanent and ubiquitous transcription of the NPM-ALK hybrid gene, resulting in the producti |
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| Immunogen | Recombinant human ALK protein fragment (aa1360-1460) |
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| Other Names | ALK Tyrosine Kinase Receptor, ALK/NPM1 fusion gene, Anaplastic lymphoma kinase Ki1, Anaplastic Lymphoma Kinase p80, anaplastic lymphoma receptor tyrosine kinase, CD246, mutant anaplastic lymphoma kinase, NBLST3, Tcrz, TFG/ALK |
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| Gene, Accession # | Gene ID: 238, Accession: Q9UM73 |
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| Catalog # | A1425-100 |
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| Price | |
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| Order / More Info | ALK Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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